March 10, 2025

Medically Reviewed by By Girish Desai, the Chief Pharmacist at Landys Chemist since 1982.

Written by Rhysa Phommachanh Head of Digital Marketing

Does Creatine Cause Hair Loss? Research & Evidence

Creatine supplements are primarily used for enhancing physical performance and muscle growth. Despite its widespread use, there are concerns that creatine supplementation might contribute to hair loss. This article examines the research surrounding the potential link between creatine, dihydrotestosterone (DHT) levels, and hair loss, along with practical tips for using creatine safely. We will also look at the evidence on how creatine affects men and women differently when it comes to hair loss.

Why Are There Concerns About Creatine and Hair Loss?

The primary concern about creatine and hair loss stems from its potential to increase levels of dihydrotestosterone (DHT), a derivative of testosterone. DHT has long been associated with androgenic alopecia, a condition responsible for male and female pattern baldness. This has led some individuals to question whether creatine supplementation could contribute to hair thinning or baldness, particularly in those who are genetically predisposed to the condition.

The link between creatine supplementation and increased DHT levels was first highlighted in a 2009 study¹ on college-aged rugby players. During the study, participants followed a three-week creatine regimen that included a 7-day loading phase (25g per day) and a 14-day maintenance phase (5g per day). The study found a significant 56% increase in DHT levels during the loading phase, which remained elevated during the maintenance phase.

While this study showed a clear increase in DHT levels, it did not assess actual hair loss among participants. Nonetheless, many experts believe this rise in DHT could contribute to hair thinning in men who are genetically predisposed to androgenic alopecia (male pattern baldness).

Research on increased DHT and hair loss in Men

DHT is a key factor in male pattern baldness (androgenic alopecia) - a process where follicles shrink, producing thinner and shorter hairs, eventually resulting in hair loss.

A 2000 study² examined scalp biopsies from men with androgenic alopecia and found higher DHT levels in areas with thinning hair, suggesting a direct correlation between DHT and follicular miniaturisation. Another study in 2001³ confirmed DHT's role in male pattern baldness, noting that inhibiting DHT production could slow hair loss or even promote hair regrowth in some men.

However, not all men with high DHT levels experience hair loss, as individual sensitivity to DHT varies, and genetics play a crucial role. While creatine supplementation has been shown to increase DHT levels, it remains unclear whether this increase significantly contributes to hair thinning in individuals without a genetic predisposition to androgenic alopecia.

Does creatine cause hair loss in women?

There is limited research directly linking creatine supplementation with hair loss in women. In women, the relationship between DHT and hair loss is less straightforward. Female pattern hair loss (FPHL) is often influenced by factors such as genetics, hormonal changes (especially around menopause), and conditions like polycystic ovary syndrome (PCOS). While some studies have noted elevated DHT levels in women with FPHL, others have not found a consistent correlation between DHT levels and hair loss.

Given the complex hormonal environment in women, the effect of creatine on DHT levels is not as predictable as it is in men. Women with PCOS, who already experience hormonal imbalances, may be more susceptible to DHT's effects on hair follicles.

Does Creatine Cause Baldness?

Creatine supplementation is generally safe for most users and does not directly cause balding. While it is true that creatine has been shown to increase DHT levels, there is no conclusive evidence that creatine supplementation will significantly contribute to hair thinning. A comprehensive review⁴ in 2021 analysed multiple studies on creatine's effect on testosterone and DHT levels. While some studies observed minor increases in testosterone, these changes were not consistent across all research. Notably, no study reported significant increases in free testosterone or instances of hair loss directly attributed to creatine supplementation.

Hair thinning is influenced by various factors, including genetics, hormonal balance, and sensitivity to DHT. As such, for most people, creatine is unlikely to cause hair loss and can be used without concerns about hair loss.

How to Use Creatine Safely

If you're concerned about hair loss but still want to take creatine, here are six ways to use it safely:

Start with a Low Dose: Begin with a smaller dose (e.g., 3-5 grams per day) to assess your body's response before considering higher doses. This can help minimise potential effects on DHT levels.
Monitor DHT Levels: Consider having your DHT levels tested before starting supplementation and periodically while using creatine. This will allow you to track any changes and make informed decisions.
Stay Hydrated: Creatine can cause water retention, so it's essential to drink plenty of water to avoid dehydration, which could exacerbate other side effects like muscle cramping and bloating.
Avoid High-Dose Loading Phases: Some people follow a loading phase (20-25g per day for 5-7 days), but skipping this step can help avoid a sudden spike in DHT levels. Instead, opt for a daily maintenance dose from the start.
Combine with DHT Blockers: Some individuals use supplements that block DHT, such as saw palmetto, to help mitigate the impact of creatine on DHT levels. We recommend trying Nutri Advanced Saw Palmetto + Stinging Nettle Complex.
Use Creatine Consistently and Moderately: Instead of using creatine in cycles (e.g., taking it for a few weeks and then stopping), it’s better to take a consistent, moderate dose over time. This can help avoid any sudden changes in your body’s DHT levels and provide more stable results.

Conclusion

There is no direct link or sufficient research to conclusively state that creatine causes hair loss. However, studies have found that creatine supplementation may lead to an increase in dihydrotestosterone (DHT) levels, and DHT is known to play a significant role in hair loss, particularly in those with a genetic predisposition. Despite this, the increase in DHT from creatine is unlikely to be significant enough to affect hair health for most individuals. For most people, creatine is safe to use without concerns about hair thinning, though those with a family history of male pattern baldness or hormonal conditions like PCOS may want to consult a healthcare provider for personalised advice.

Pharmacist Neesha Desai from Landy’s Chemist adds, “While creatine is generally safe for most people, if you are concerned about hair loss, especially with a family history of androgenic alopecia, it’s best to consult a healthcare professional before starting supplementation.”

Creatine and Hair Loss Summary:

There is no evidence that creatine causes hair loss in women and men
The only link between creatine and hair loss is that it may increase DHT
Taking creatine 5g daily dose is not enough to cause a significant rise in DHT

Frequently Asked Questions

Does Creatine Cause Hair Loss in Females?

The research on creatine and hair loss in women is limited. While some women with conditions like PCOS, which is associated with higher androgen levels, may be more susceptible to hair thinning, there is no definitive evidence linking creatine directly to hair loss in women. The effects may vary depending on individual hormonal factors.

Does 5g creatine increase DHT?

Yes, 5g of creatine can increase DHT levels, but the increase is generally small. Research⁵ has shown that creatine supplementation, particularly in the loading phase, can lead to a temporary rise in DHT levels. However, the increase in DHT with a 5g daily dose is not as significant as higher doses used in loading phases (20-25g per day). While DHT is linked to hair loss in individuals genetically predisposed to androgenic alopecia, the effect of a 5g dose on hair health is unlikely to be large enough to cause noticeable hair thinning for most users.

Are Certain People More Prone to Hair Loss From Creatine?

Individuals who are genetically predisposed to androgenic alopecia (male or female pattern baldness) may be more prone to experiencing hair thinning when taking creatine due to the increase in DHT levels. Additionally, women with hormonal imbalances, such as those with PCOS, may also be more sensitive to the effects of creatine on hair health.

Is there a way to prevent hair loss from creatine?

Yes, taking saw palmetto, a natural DHT blocker, may help reduce the risk of hair loss associated with creatine supplementation by mitigating DHT's effects on hair follicles. A study⁶ found that participants using saw palmetto supplements experienced a 60% improvement in hair quality, compared to 11% in the placebo group.

References

Disclaimer:

This article is for informational purposes only and is not a substitute for medical advice. Consult your doctor or healthcare provider before starting any supplements, treatments, or remedies. Ensure a varied and balanced diet and a healthy lifestyle before considering supplements. Supplements should not replace a balanced diet.